Abstract
Sema3E, a ligand for PlexinD1, controls angiogenesis and promotes cancer invasion and metastasis. In this issue of Cancer Cell, Luchino and colleagues report that Sema3E also ensures breast cancer cell viability byblocking a previously unknown proapoptotic signaling cascade elicited by unliganded PlexinD1, thus behaving as a "dependence receptor.". © 2013 Elsevier Inc.
Lingua originale | English |
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pagine (da-a) | 564-566 |
Numero di pagine | 3 |
Rivista | Cancer Cell |
Volume | 24 |
Numero di pubblicazione | 5 |
DOI | |
Stato di pubblicazione | Pubblicato - 2013 |
Keywords
- Cancer Research
- Cell Biology
- Oncology